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International Journal of Mass Spectrometry
Copyright © 2004 Elsevier B.V. All rights reserved

Volume 238, Issue 2, Pages 75-206 (1 November 2004)
Drug Discovery

Edited by Steven A. Hofstadler and Mike S. Lee
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1.
Editorial EDITORIAL
Page 75
Steven A. Hofstadler and Mike S. Lee
SummaryPlus | Full Text + Links | PDF (30 K)
2.
An affinity selection–mass spectrometry method for the identification of small molecule ligands from self-encoded combinatorial libraries: Discovery of a novel antagonist of E. coli dihydrofolate reductase ARTICLE
Pages 77-83
D. Allen Annis, John Athanasopoulos, Patrick J. Curran, Jason S. Felsch, Krishna Kalghatgi, William H. Lee, Huw M. Nash, Jean-Paul A. Orminati, Kristin E. Rosner, Gerald W. Shipps et al.
SummaryPlus | Full Text + Links | PDF (239 K)
3.
SFC/MS in drug discovery at Pfizer, La Jolla ARTICLE
Pages 85-97
Ben Bolaños, Michael Greig, Manuel Ventura, William Farrell, Christine M. Aurigemma, Haitao Li, Terri L. Quenzer, Kathleen Tivel, Jessica M.R. Bylund, Phuong Tran et al.
SummaryPlus | Full Text + Links | PDF (624 K)
4.
Using mass spectrometry to study the photo-affinity labeling of protein tyrosine phosphatase 1B ARTICLE
Pages 99-106
Tammy LeRiche, Kathryn Skorey, Patrick Roy, Dan McKay and Kevin P. Bateman
SummaryPlus | Full Text + Links | PDF (207 K)
5.
Generic approach to high throughput ADME screening for lead candidate optimization ARTICLE
Pages 107-117
J.L. Herman
SummaryPlus | Full Text + Links | PDF (231 K)
6.
An integrated strategy for the discovery of drug targets by the analysis of protein–protein interactions ARTICLE
Pages 119-130
John M. Peltier, Srdjan Askovic, Robert R. Becklin, Cindy Lou Chepanoske, Yew-Seng J. Ho, Vladimir Kery, Shuping Lai, Tahmina Mujtaba, Mike Pyne, Paul B. Robbins et al.
SummaryPlus | Full Text + Links | PDF (496 K)
7.
Effective strategies for the development of specific, sensitive and rapid multiple-component assays for cassette dosing pharmacokinetic screening ARTICLE
Pages 131-137
Ron Huang, Mark Qian, Susan Chen, Peter Lodenquai, Hang Zeng and Jing-Tao Wu
SummaryPlus | Full Text + Links | PDF (206 K)
8.
Quantitative bioanalysis: an integrated approach for drug discovery and development ARTICLE
Pages 139-152
Voon S. Ong, Kevin L. Cook, Christine M. Kosara and William F. Brubaker
SummaryPlus | Full Text + Links | PDF (239 K)
9.
High throughput HPLC/MS purification in support of drug discovery ARTICLE
Pages 153-162
W. Goetzinger, X. Zhang, G. Bi, M. Towle, D. Cherrak and J.N. Kyranos
SummaryPlus | Full Text + Links | PDF (411 K)
10.
Differential expression profiling of serum proteins and metabolites for biomarker discovery ARTICLE
Pages 163-171
Sushmita Mimi Roy, Markus Anderle, Hua Lin and Christopher H. Becker
SummaryPlus | Full Text + Links | PDF (453 K)
11.
MALDI-TOF MS: a platform technology for genetic discovery ARTICLE
Pages 173-188
Dirk van den Boom, Martin Beaulieu, Paul Oeth, Rich Roth, Christiane Honisch, Matthew R. Nelson, Christian Jurinke and Charles Cantor
SummaryPlus | Full Text + Links | PDF (657 K)
12.
Improved protein identification using automated high mass measurement accuracy MALDI FT-ICR MS peptide mass fingerprinting ARTICLE
Pages 189-196
David M. Horn, Eric C. Peters, Heath Klock, Andrew Meyers and Ansgar Brock
SummaryPlus | Full Text + Links | PDF (200 K)
13.
High throughput drug discovery with ESI-FTICR ARTICLE
Pages 197-206
Kristin A. Sannes-Lowery, Lendell L. Cummins, Shuo Chen, Jared J. Drader and Steven A. Hofstadler
SummaryPlus | Full Text + Links | PDF (191 K)
14.
Title/Editorial board EDITORIAL BOARD
Page i

PDF (42 K)
15.
Forthcoming Articles MISCELLANEOUS
Page I

PDF (34 K)

Issue List
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